Fumi Kubo, Ph.D.

Research Overview

Animals generate behaviors depending on sensory information that they receive from the outside world. Using zebrafish as a model, our lab studies the neural circuit mechanisms for how goal-directed behaviors are generated by ongoing and past sensory information. Taking advantage of the zebrafish system, we take exhaustive approaches and aim to understand the roles of genetically defined neuron types and their circuit connectivity within the entire brain.

Main Research Fields

Biology

Related Research Fields

Interdisciplinary Science & Engineering / Biological Sciences / Neuroscience-general-related / Function of nervous system-related / Animal physiological chemistry, physiology behavioral biology-related

Keywords

• Sensory processing
• Sensorimotor transformation
• Neural circuits
• Zebrafish

Selected Publications

Papers with an asterisk(*) are based on research conducted outside of RIKEN.

1. * Svara F, Förster D, Kubo F, Januszewski M, dal Maschio M, Schubert PJ, Kornfeld J, Wanner AA, Laurell E, Denk W, Baier H.
   "Automated synapse-level reconstruction of neural circuits in the larval zebrafish brain."
   Nature Methods 19, 1357–1366. (2022)
   10.1038/s41592-022-01621-0
2. * Matsuda K and Kubo F.
   "Circuit organization underlying optic flow processing in zebrafish"
   Front. Neural Circuits 15, 709048. (2021)
   10.3389/fncir.2021.709048
3. * Wu Y, dal Maschio M, Kubo F, Baier H.
   "An optical illusion pinpoints an essential circuit node for global motion processing"
   Neuron 108, 722-734. (2020)
   10.1016/j.neuron.2020.08.027
4. * Kramer A, Wu Y, Baier H, Kubo F.
   "Neuronal architecture of a visual center that processes optic flow."
   Neuron 103, 118-132. (2019)
   10.1016/j.neuron.2019.04.018
5. * Kunst M, Laurell E, Mokayes N, Kramer A, Kubo F, Fernandes AM, Förster D, Dal Maschio M, Baier H.
   "A Cellular-Resolution Atlas of the Larval Zebrafish Brain."
   Neuron 103, 21-38. (2019)
   10.1016/j.neuron.2019.04.034
6. * Förster D, Kramer A, Baier H, Kubo F.
   "Optogenetic precision toolkit to reveal form, function and connectivity of single neurons."
   Methods 50, 42-48. (2018)
   10.1016/j.ymeth.2018.08.012
7. * Förster D, Arnold-Ammer I, Laurell E, Barker AJ, Fernandes AM, Finger-Baier K, Filosa A, Helmbrecht T, Kölsch Y, Kühn E, Robles E, Slanchev K, Thiele T, Baier H, Kubo F.
   "Genetic targeting and anatomical registration of neuronal populations in the zebrafish brain with a new set of BAC transgenic tools."
   Scientific Reports 7, 5230. (2017)
   10.1038/s41598-017-04657-x
8. * Kubo F, Hablitzel B, Dal Maschio M, Driever W, Baier H, Arrenberg AB.
   "Functional architecture of an optic flow responsive area that drives horizontal eye movements in zebrafish."
   Neuron 81, 1344-59. (2014)
   10.1016/j.neuron.2014.02.043